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Active Polyphenol In Turmeric Inhibits Metastasis Of Prostate Cancer Cells

October 12, 2012: 12:00 AM EST
German and Italian scientists who tested the effect of curcumin, the active polyphenol in the spice turmeric responsible for the color of curry, in mouse models of prostate cancer found that it inhibits the spread of the cells, a process known as metastasis. For the study, researchers examined the molecular processes that go haywire in prostate carcinoma cells, finding that cancer cells produce proteins that promote inflammation. Curcumin, however,  decreased the expression of the proteins, and this correlated with a decline in metastases in the mice.
P. H. Killian et al., "Curcumin Inhibits Prostate Cancer Metastasis in vivo by Targeting the Inflammatory Cytokines CXCL1 and -2", Carcinogenesis, October 12, 2012, © Killian et al.
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