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Evidence Suggests Vitamin C May Someday Be Used To Treat Cancer

March 8, 2017: 12:00 AM EST
British researchers who tested the effect of several substances, including natural compounds, on cancer stem cells found that vitamin C was significantly better at stopping cell growth. The researchers tested seven substances in the lab: the clinically-approved drug stiripentol, three natural products – caffeic acid phenyl ester (CAPE), silibinin and ascorbic acid (vitamin C) – and experimental pharmaceuticals actinonin, FK866 and 2-Deoxy-D-glucose molecule (2-DG). Vitamin C was found to be ten times more effective at stopping cancer stem cell growth than pharmaceuticals. The researchers believe vitamin C inhibits glycolysis in cancer stem cells, the process that fuels energy production in mitochondria, the "powerhouse" of the cell. [ Image credit: © NIH/ODS ]
Gloria Bonuccelli et al., "NADH autofluorescence, a new metabolic biomarker for cancer stem cells: Identification of Vitamin C and CAPE as natural products targeting “stemness”", Oncotarget, March 08, 2017, © Bonuccelli et al.
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