Higher BMI Increases Risk Of Gallstone Disease

July 11, 2013: 12:00 AM EST

Although earlier studies have shown a strong association between a greater body mass index and greater risk gallstone disease, new Danish research has determined a significant causal relationship between the two. Gallstones are a pebble-like material that can develop when there is excess cholesterol –- accounting for 80 percent of all gallstones – bile salts or bilirubin in bile stored in the gallbladder. Researchers studied health data from nearly 78,000 people over 34 years. Findings indicated that gallstone disease risk increased 7 percent for every 1 kg/m2 increase in BMI.

Stefan Stender et al., "Elevated body mass index as a causal risk factor for symptomatic gallstone disease: A mendelian randomization study", Hepatology, July 11, 2013, © John Wiley & Sons, Inc.

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Higher BMI Increases Risk Of Gallstone Disease

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