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Mouse Study Finds That Viagra Converts White Fat Cells To Obesity-Fighting Beige Cells

January 17, 2013: 12:00 AM EST
German researchers who tested the effect of sildenafil – better known as the erectile dysfunction drug Viagra – found that in mice it increased the conversion of problematic white fat cells into obesity-fighting beige ones. The researchers had known for some time that mice fed a high-fat diet did not gain weight when taking sildenafil. But they didn’t know why. The new study notes that sildenafil converts white fat cells into beige fat cells that burn energy from ingested food and convert it to heat. The beige fat cells “melt the fat” and thus fight obesity.
M. M. Mitschke et al., " Increased cGMP promotes healthy expansion and browning of white adipose tissue", The FASEB Journal, January 17, 2013, © FASEB
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