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Scientists Track Changes In Gene Expression Induced By Variations In Diet

March 28, 2013: 12:00 AM EST
In an animal study, U.S. researchers found that even the smallest changes in diet produce differences in gene expression linked to physiological changes. When transparent roundworms of the species C. elegans were fed different types of bacteria, their gene expression programs changed dramatically: one diet variation led to fewer offspring, shorter lives and faster development than a standard diet. The researchers said that use of a “very tractable system” like the roundworm may allow scientists to pinpoint precise questions about how certain foods could effect gene expression, physiological traits and disease in humans.
Lesley T. MacNeil et al., "Diet-Induced Developmental Acceleration Independent of TOR and Insulin in C. elegans", Cell, March 28, 2013, © Elsevier Inc.
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