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Selenium And Vitamin E Prove A Dangerous Combination For Men

February 21, 2014: 12:00 AM EST
Data derived from a seven-year, multicenter, 35,000-men clinical trial show that selenium and vitamin E not only do not protect against prostate cancer, they actually increase the risk. At the start of the trial in 2001, U.S. researchers measured the concentration of selenium in participants to see whether selenium supplements would benefit men with low levels. They instead found  that taking selenium increased the risk of high-grade cancer by 91 percent among men with high selenium status at baseline. In addition, taking vitamin E increased cancer risk in men with low selenium at the beginning by 63 percent and increased the risk of high-grade cancer by 111 percent.
Alan R. Kristal et al., "Baseline Selenium Status and Effects of Selenium and Vitamin E Supplementation on Prostate Cancer Risk", Journal of the National Cancer Institute, February 21, 2014, © Kristal et al.
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