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Study Shows Potential Effectiveness Of Cork Tree Bark Extract In Treating Prostate Cancer

March 3, 2014: 12:00 AM EST
A species of cork tree found in eastern Asian countries and long used in Chinese herbal medicines may play a significant role in the treatment of both pancreatic and prostate cancer,  U.S. researchers report. In the study it was found that an extract (Nexrutine) of the Amur cork tree bark blocks cancer tumor development pathways (proteins) that are similar in the pancreas and the prostate. The extract inhibits the scarring (fibrosis) around the tumors that thwart the entry of anti-cancer drugs, hindering effective treatment. Nexrutine has already been shown to be both safe and effective in a clinical trial involving 24 prostate cancer patients.
J. Gong et al., "Combined Targeting of STAT3/NF- B/COX-2/EP4 for Effective Management of Pancreatic Cancer", Clinical Cancer Research, March 03, 2014, © American Association for Cancer Research
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