We use our own and third-party cookies to optimize your experience on this site, including to maintain user sessions. Without these cookies our site will not function well. If you continue browsing our site we take that to mean that you understand and accept how we use the cookies. If you wish to decline our cookies we will redirect you to Google.
Already have an account? Sign in.

 Remember Me | Forgot Your Password?

Vitamin A Derivative Shows Potential In Fighting Obesity, Diabetes

June 16, 2014: 12:00 AM EST
Canadian researchers have demonstrated in mice the benefits of using retinoic acid, a derivative of vitamin A, in treating obesity and type 2 diabetes. The study found that retinoic acid reduced the risk of cardiac apoptosis (cell death) in obese and insulin-resistant mice, stimulated the expression of cardio-protective genes reduced by the disease, and protected against the accumulation of collagen in heart muscle. Collagen accumulation is associated with fibrosis and future complications.  The scientists said the findings spotlight  new metabolic effects of retinoids and could lead to development of anti-obesity and anti-diabetic medicines.
Daniel-Constantin Manolescu et al., "All-trans retinoic acid stimulates gene expression of the cardio-protective natriuretic peptide system, and prevents fibrosis and apoptosis in cardiomyocytes of obese ob/ob mice. ", Applied Physiology, Nutrition, and Metabolism, June 16, 2014, © Canadian Science Publishing
Domains
HEALTH & WELLNESS
Body
Conditions
Food & Nutrition
Heart & Cardiovascular
Preventative Care
Vitamins
Diabetes
Geographies
Worldwide
North America
Canada
Categories
Research, Studies, Advice
Developed by Yuri Ingultsov Software Lab.