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Vitamin B3 Found To Counteract Muscle Degeneration Of Muscular Dystrophy

October 23, 2012: 12:00 AM EST
A U.S. study in zebrafish models of muscular dystrophy has found that muscle structure and function were improved by supplying a common cellular chemical – or its precursor vitamin B3 – to activate a cell adhesion pathway. Activation of the pathway counteracts the muscle degeneration ad reduced mobility caused by muscular dystrophies. The researchers said that their findings are especially important for congenital muscular dystrophies, which are progressive,  debilitating and often lethal.
Michelle F. Goody et al., "NAD Biosynthesis Ameliorates a Zebrafish Model of Muscular Dystrophy", PLoS Biology, October 23, 2012, © Goody et al.
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