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Low Doses Of Resveratrol Effectively Check Tumor Growth In Mice

August 19, 2015: 12:00 AM EST
A low rather than a high dose of the antioxidant resveratrol prevents tumor growth in mice and alters metabolic pathways in human tissues, a study by British and U.S. researchers has found. Earlier studies looked at the impact of high doses of resveratrol, a compound found in red grapes and wine, on cancer prevention. This study analyzed the effects of a lower daily dose – the amount of resveratrol found in a large (250 ml, or 8.5 ounce) glass of red wine – compared to a dose 200 times higher. The researchers cautioned that drinking a glass of wine a day will not necessarily prevent cancer. The problem: you can’t separate resveratrol in wine from the alcohol which itself can be cancer-inducing. Much more research is needed, they said.
H. Cai et al., "Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice. ", Science Translational Medicine, August 19, 2015, © American Association for the Advancement of Science
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