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Omega-3 Fatty Acid Reverses Fructose-Caused Genetic Damage

May 18, 2016: 12:00 AM EST
A U.S. study finds that the omega-3 fatty acid DHA (docosahexaenoic acid) reverses the harmful changes to hundreds of genes, especially in the brain, caused by consumption of the common sugar fructose. Diseases linked to fructose-induced genetic changes include diabetes, cardiovascular disease, Alzheimer's disease, and attention deficit hyperactivity disorder (ADHD). DHA, however, changes the entire gene pattern back to normal, researchers said, and strengthens synapses in the brain associated with learning and memory. DHA occurs naturally in brain cells, but there is not enough of it to ward off diseases. So it has to come through diet. It is abundant in wild (not farmed) salmon and some other fish and fish oil, as well as walnuts, flaxseed, fruits, and vegetables.
Qingying Meng et al., "Systems Nutrigenomics Reveals Brain Gene Networks Linking Metabolic and Brain Disorders. ", EBioMedicine, May 18, 2016, © Meng et al.
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