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Omega-3s Prevent Adverse Vascular Effects Of Heart Surgery

May 30, 2013: 12:00 AM EST
Compounds derived from polyunsaturated fatty acids known as omega-3s reduce cardiovascular inflammation and improve healing after procedures like angioplasty, stenting and heart bypass surgery, a new U.S. study has found. Inflammation and scarring after such procedures can lead to permanent disability and even death. For the study, researchers tested the effects of the compounds (resolvin or RvD) in cultured vascular cells taken from patients who had undergone bypass operations, and then in rabbits treated with balloon angioplasty. The compounds dramatically reduced inflammation, cell migration, and cell growth (scarring) in vascular smooth muscle cells.
T. Miyahara et al., "D-series resolvin attenuates vascular smooth muscle cell activation and neointimal hyperplasia following vascular injury", The FASEB Journal, May 30, 2013, © Federation of American Societies for Experimental Biology
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