Though some research has shown that mom's unhealthful diet in pregnancy may preordain a child’s poor diet and health issues, a new study in mice suggests other factors play a bigger role. Having too many food choices, the U.S. researchers found, increases the obesity problem. For the study, two sets of mothers were fed a high-fat diet or a low-fat diet. The offspring then ate a high-fat diet, low-fat diet, or a choice of foods. The offspring that had a choice experienced an increase in body weight, body fat, and glucose levels. The researchers said their findings suggest the possibility that a human's natural environment can affect food choices, and ultimately a person's weight, much more than their mother’s diet during pregnancy.
"Mitigating or Exacerbating Effects of Maternal-Fetal Programming of Female Mice Through the Food Choice Environment. ", Endocrinology, March 07, 2015
Fasting has been shown in animal studies to extend lifespan and thwart diseases related to aging. Now U.S. researchers have shown that a feast-or-famine – or intermittent fasting – diet pattern offers some of the same benefits of long-term fasting for people, though the benefits may be lost in the presence of antioxidants. Intermittent fasting causes oxidative stress, which activates a protein called SIRT3 that, when increased in mice, extends lifespan. In a small clinical study, SIRT3 was indeed activated by intermittent fasting, but the benefits vanished when high levels of antioxidants were added to the diet. This reinforces research that has shown that flooding the system with supplemental antioxidants neutralizes the benefits of fasting or exercise.
"Practicality of Intermittent Fasting in Humans and its Effect on Oxidative Stress and Genes Related to Aging and Metabolism. ", Rejuvenation Research, March 07, 2015
A German study in mice has found that a high-salt diet, normally considered risky for heart health, protects tissues from microbial infections. A diet rich in sodium has been proven time and again to be detrimental for cardiovascular diseases. Recent studies have shown that it also worsens autoimmune diseases. But the researchers became intrigued when they noticed a high concentration of salt in the infected skin of mice bitten by cage mates. They also noted that human patients with bacterial skin infections showed remarkably high salt accumulation at the lesion sites. While not recommending a salty diet, the researchers nevertheless said salt supplementation might provide a therapeutic option when there is too little of it at infection sites.
"Cutaneous Na Storage Strengthens the Antimicrobial Barrier Function of the Skin and Boosts Macrophage-Driven Host Defense. ", Cell Metabolism, March 07, 2015
A U.S. study among 374 heart attack patients within weeks of the infarction found that taking a prescription-strength omega-3 supplement (Lovaza, 4,000 mg) lowered inflammation and seemed to protect against further declines in heart function. Researchers used cardiac magnetic resonance imaging to look at changes in patients' hearts and see the disease process before and after treatment. The researchers acknowledged that the study did not explore the association between omega-3 fatty acids and post-attack cardiac events, nor did it evaluate the treatment immediately after a heart attack.
"Omega 3 fatty acids appear to protect damaged heart after heart attack", News release, study presented at the American College of Cardiology’s annual scientific session, March 04, 2015
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Nutrition Insight, March 06, 2015
Mary Ann Liebert Publishers, March 01, 2015
EurekAlert!, February 26, 2015
Science Daily, February 26, 2015
The New York Times, February 25, 2015
Nutrition Insight, February 24, 2015
The New York Times, February 23, 2015
Nutrition Insight, February 20, 2015
Nutraceuticals World, February 20, 2015
Journal of the International Society of Sports Nutrition, February 19, 2015
Gizmag, February 19, 2015
Chicago Tribune, February 15, 2015
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