Scientists have suspected for awhile that there’s a link between multivitamin supplements and healthy eyes, but there was no reliable scientific data to support the theory. Now researchers at Harvard report results from a randomized, double-blind study from 1997 to 2011 of 14,641 U.S. male doctors age 50 and older, half of whom took a common daily multivitamin, plus vitamin C, vitamin E and beta carotene supplements. Half took a placebo. In the placebo group there were 945 cases of cataract, but only 872 cases in the multivitamin group, a nine percent decrease in risk. The risk was 13 percent for nuclear cataract, the most common variety of cataract associated with the aging process.
"Effects of Multivitamin Supplement on Cataract and Age-Related Macular Degeneration in a Randomized Trial of Male Physicians", Ophthalmology, February 20, 2014
A 28-year Finnish study of twins finds that a sensation of breathlessness – known as dyspnea – during light daily activities can be an indicator of a higher risk of death. It is definitely is an indicator of exercise intolerance and low fitness. In the study, twins with persistent dyspnea (first noticed in 1975 and 1981) and dyspnea developers (dyspnea noticed in 1981) had an increased risk of death compared to individuals without dyspnea symptoms. Easy shortness of breath also indicated an increased risk of death among individuals considered healthy at the 1981 baseline.
"Dyspnea and All-Cause Mortality: 28-Year Follow-up Study among Adult Twins. ", Medicine & Science In Sports & Exercise, February 20, 2014
People with chronic obstructive pulmonary disease (COPD) could reduce the time spent in the hospital with severe respiratory attacks if they would start walking every day, a Spanish study has found. COPD includes chronic bronchitis and emphysema and is characterized by breathing difficulties resulting from long-term lung damage, often from smoking. For the study, researchers monitored the exercise levels of 543 COPD patients. They found that those who maintained moderate or high levels of exercise over time – including low intensity activities such as walking two to four miles a day – reduced the likelihood of being hospitalized by severe symptoms.
" Influence of changes in physical activity on frequency of hospitalization in chronic obstructive pulmonary disease", Respirology, February 18, 2014
A British study that compared same-age, same-sex babies in the same family revealed that a hearty appetite, and unresponsiveness to satiety signals, in infancy may be a portent of future obesity. The researchers analyzed data – measures of satiety responsiveness and food responsiveness – from non-identical, same-sex twins born in the U.K. in 2007. Infant twins who were more food responsive or less satiety responsive grew faster than their co-twins. The researchers advised parents to be alert for these tendencies because this behavior could put a growing child at risk of gaining weight too fast, putting on an unhealthy amount of weight, and being obese as an adult.
"Satiety Mechanisms in Genetic Risk of Obesity", JAMA Pediatrics, February 17, 2014
A pilot project involving 83 menopausal women found that five consultative doctor visits over six months, combined with health risk assessment, exercise, and other factors, helped the women fight obesity and reduce hot flashes. At the end of the U.S. project, the participants, aged 35 to 55, better understood their health risks and set and achieved health goals. They trimmed their waistlines by an average of 1.5 inches and lowered their diastolic blood pressure by two points; hot flashes and other menopause symptoms – energy, libido, mood, vaginal dryness, etc. – had all improved significantly. All of the visits to their healthcare provider were reimbursed by insurance.
"Clinical intervention to reduce central obesity and menopausal symptoms in women aged 35 to 55 years", Menopause, February 13, 2014
A U.S. study using accelerometry-based technology to validate a protocol for calculating energy expenditure found that obese Americans on average spend less than a minute a day on vigorous exercise, and 15 hours sleeping and sitting. The technology could prove to be an effective way to supplant the use of questionnaire data for estimating lifestyle factors, like exercise and diet, in research. The study of 1,272 men and 1,325 women found that obese particpants were significantly less physically active and spent more time in sedentary behaviors than their normal weight counterparts.
"Validation of a Novel Protocol for Calculating Estimated Energy Requirements and Average Daily Physical Activity Ratio for the US Population: 2005-2006", Mayo Clinic Proceedings, February 12, 2014
The molecule N-acetyl-aspartate (NAA) in the hippocampus is associated with brain health. The hippocampus is involved in memory, learning, appetite control and emotions. In this study, U.S. researchers using magnetic resonance spectroscopy were able to visualize the NAA molecule in the hippocampus, finding that overweight participants had lower levels in their brains than normal weight participants, an effect independent of age, sex or psychiatric diagnoses. The researchers acknowledged further research is needed because they didn’t whether "low NAA is a consequence of being overweight, causes being overweight, or is a combination of both”.
"Reduced hippocampal N-acetyl-aspartate (NAA) as a biomarker for overweight", NeuroImage: Clinical, February 11, 2014
A therapy that combines vitamin C injections with conventional chemotherapy (carboplatin and paclitaxel) stopped ovarian cancer in Petri dish cells, animals and humans, U.S. researchers report. In addition, the therapy reduced chemotherapy- associated toxicity in patients. The researchers said intravenous, but not oral, vitamin C kills some cancer cells without harming normal tissues. The clinical trial involved 27 patients with newly diagnosed stage 3 or stage 4 ovarian cancer. All received conventional chemotherapy, and some received high-dose intravenous vitamin C. Patients were monitored for five years. Patients who received vitamin C experienced reduced cancer as well as fewer toxic effects from chemotherapy drugs.
"High-Dose Parenteral Ascorbate Enhanced Chemosensitivity of Ovarian Cancer and Reduced Toxicity of Chemotherapy", Science Translational Medicine, February 10, 2014
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The New Old Age, February 19, 2014
Norwegian Institute of Public Health, February 18, 2014
The New York Times, February 12, 2014
Annals of Allergy, Asthma & Immunology, February 07, 2014
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