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Subject:
HEALTH & WELLNESS
Period: March 15, 2014 to April 1, 2014
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Worldwide
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Contents
 

Medical Marijuana Provides Some Symptom Relief In Multiple Sclerosis

The American Academy of Neurology has published a new guideline stating that medical marijuana pills and oral sprays do ease the symptoms of people with multiple sclerosis, including spasticity, pain from spasticity and frequent urination. The guideline looked at other so-called complementary and alternative medicine (CAM) therapies for MS, finding no evidence of therapeutic value. Other nonconventional therapies included ginkgo biloba, magnetic therapy, bee sting therapy, omega-3 fatty acids and reflexology. The researchers noted that the marijuana-based therapies often have adverse side effects and should be taken only with the advice of physicians. The FDA has approved certain synthetic marijuana ingredients for treatment of some disease symptoms and drug side effects.

"Summary of evidence-based guideline: Complementary and alternative medicine in multiple sclerosis: Report of the Guideline Development Subcommittee of the American Academy of Neurology. ", Neurology, March 24, 2014

Supplements Are Not The Only Viable Source Of Healthful Vitamin E

Vitamin E has been shown to improve age-related diseases and conditions, like Alzheimer’s and macular degeneration. That fact, and the growing proportion of older people in the world, led Swiss vitamin supplier DSM to recently call for a substantial increase in the recommended daily intake (RDI) of vitamin E. But supplements are not the only viable source, Euromonitor says. The two most common food sources are gamma-tocopherol – found in corn oil, soybean oil and margarine – and alpha-tocopherol, found in wheat germ oil, sunflower and safflower oils, as well as sunflower seeds, almonds, hazelnuts and peanuts. According to Euromonitor, in 2012 nearly 1,500 tons of vitamin E were consumed in food and drink products, of which 40 percent came from oils and fats.

"Increasing Vitamin E Intake: No Need to Rely Solely on Supplements", Euromonitor International, March 21, 2014

Teaching People How To Substitute Herbs And Spices Reduces Salt Intake

A two-phase U.S. clinical study in which participants were taught strategies for substituting herbs and spices for salt found that those involved in the intervention learned to consume healthier levels of sodium. More than 60 percent of the participants had high blood pressure, 18 percent had diabetes; all were overweight. In phase 1 of the study, all participants ate a low-sodium diet for four weeks, reducing average sodium intake by half. In phase 2, half of the participants spent 20 weeks learning how to use herbs and spices in recipes, how to make low-sodium intake permanent, etc. Those in the intervention group consumed on average 966 mg less sodium daily than the control group, indicating that the coaching process was a more effective way to reduce sodium intake.

"Spices and herbs intervention helps adults reduce salt intake", News release, research presented at the American Heart Association scientific sessions on nutrition and metabolism, March 19, 2014

Scientists Explain Why Dark Chocolate Is So Good For You

Louisiana State University chemists recently told a scientific meeting that dark chocolate is healthful because good microbes (e.g., Bifidobacterium and lactic acid bacteria) in the intestines “feast on chocolate”, growing it, fermenting it and producing compounds that fight inflammation. When absorbed by the body, the compounds reduce cardiovascular inflammation and cut the long-term risk of stroke. But how? It seems that cocoa powder, found in dark chocolate, contains several polyphenolic (antioxidant) compounds such as catechin and epicatechin, as well as some dietary fiber. None of these are well-digested or absorbed. But when they reach the colon, the beneficial bacteria do their job.

"The precise reason for the health benefits of dark chocolate: mystery solved.", News release, presentation at the American Chemical Society annual meeting., March 18, 2014

Omega-3 Supplements Do Not Reduce Risk Of Cardiovascular Disease Among The Elderly

Older people who took part in a five-year U.S. clinical trial testing the impact of omega-3 supplementation for age-related macular degeneration did not show a reduced risk of cardiovascular disease. The supplements contained, besides omega-3 fatty acids found in fish oils, the dietary xanthophylls lutein and zeaxanthin, found in green leafy vegetables and in the macula of the human eye. The data showed no significant cardiovascular benefit among older individuals treated with either omega-3 supplements or with a combination of lutein plus zeaxanthin. The results are consistent with mounting evidence from clinical trials, the researchers said.

"Effect of Long-Chain omega-3 Fatty Acids and Lutein Zeaxanthin Supplements on Cardiovascular Outcomes. ", JAMA Internal Medicine, March 18, 2014

Positive Memories Of Exercise Are Powerful Motivators To Lead Healthier Lifestyle

U.S. researchers have determined that positive memories of exercising are a good way to get motivated to adopt a healthier lifestyle. The researchers asked 150 students to remember either a positive or negative memory that would increase their motivation to exercise. A control group of students was not asked to recall a motivational memory. The students were asked a week later whether they had increased the time spent exercising. Students who remembered a positive exercise memory reported much higher levels of subsequent exercise than those who were not asked to recall a memory about exercise.

"Using memories to motivate future behavior: An experimental exercise intervention. ", Memory, March 17, 2014

Agave Sugar May Be Answer To A Type 2 Diabetic’s Prayer

Mexican researchers have determined that a natural form of sugar found in the agave plant – used to distill tequila –  may help people with type 2 diabetes lose weight because, though sweet-tasting, they not digestible and therefore act as a dietary fiber that reduces blood glucose levels. Agavins also increase levels of a hormone that stimulates production of insulin. Agavins are not expensive, have no known side effects, and help support the growth of healthful microbes in the mouth and intestines. Agavins should not be confused with agave nectar or agave syrup (found in health food stores) that contain fructans sugars similar to high fructose corn syrup.

"Tequila plant possible sweetener for diabetics, helps reduce blood sugar, weight.", News release, presentation at the American Chemical Society annual meeting., March 16, 2014

Older People Should Focus Less On Weight, Body Mass, More On Building Muscle

New U.S research confirms that building muscle mass, especially as we age, is important in decreasing metabolic risk. The study analyzed data collected between 1988 and 1994 on 3,659 men 55 or older and women 65 or older. Measuring body composition and associating it with death rates, they found that the greater the muscle mass, the lower the risk of death. In other words, people should be worried less about weight and body mass index and more about maximizing and maintaining muscle mass.  The researchers advise physicians to keep these findings in mind when counseling older adults about behavior that might improve health.

"Muscle Mass Index as a Predictor of Longevity in Older-Adults. ", The American Journal of Medicine, March 14, 2014

Study Answers The Question: Should I Do Cardio Or Left Weights First For Maximum Benefit?

This study by Finnish researchers was set up to determine whether it mattered what order a person does cardio or strength exercises. Are the exercises more effective at increasing performance or muscle mass one way or the other? Participants were men 18 to 40 years old who did two to three supervised cardio and resistance training sessions a week, regularly reversing the order over 24 weeks. The researchers found differences in recovery times for the differently-sequenced routines, but ultimately found that the order of the different routines “does not lead to differences in the adaptations of overall fitness and body composition”. No matter which exercise was performed first, physical performance and muscle size increased during the study “to about a similar extent”.

"The order effect of combined endurance and strength loadings on force and hormone responses: effects of prolonged training. ", European Journal of Applied Physiology, March 13, 2014

Big Waist Takes Years Off Men’s And Women’s Lives

Men and women with big bellies are more likely to die years earlier than smaller-waist people, and more likely to die from heart disease, respiratory problems, and cancer after accounting for body mass index, smoking, alcohol use and physical activity, U.S. researchers have found. After analyzing 11 studies involving 600,000 people from around the world, the researchers noted that men over 40 with waists of 43 inches or more were 50 percent more likely to die three years earlier than men with waists less than 35 inches. Women with a 37-inch waist or larger had about an 80 percent higher risk of dying than women with a 27-inch or smaller waist. The larger waist in women over 40 takes five years off their lives.

"A Pooled Analysis of Waist Circumference and Mortality in 650,000 Adults. ", Mayo Clinic Proceedings, March 12, 2014

Drinking Two Quarts Of Water A Day Does Not Contribute To Weight Loss

Just about every diet plan recommends drinking a lot of water – usually eight 8-oz. glasses a day – to reduce appetite and help burn calories. But a nutrition professor at the University of Alabama could find no scientific evidence that drinking a lot of water leads to weight loss. She acknowledges that people need to drink plenty of fluids during the day, but they can come from many sources: diet soda, green tea, juice, powdered beverages mixed with water and, yes, plain water. Caffeinated beverages like coffee and tea also count, and they do hydrate. For weight loss, Beth Kitchin suggests long-term, science-based weight management programs like EatRight (by UA-Birmingham) or Volumetrics.

"Debunking water myths: Weight loss, calorie burn and more", News release, University of Alabama, Birmingham, March 12, 2014

Bread, Cereals Contribute Heavily To Elevated Salt Consumption Among British Children

A British study finds that children in London eat way too much salt, and they get it from some surprising sources. Researchers analyzed urine samples from 340 children aged five to 17. Five and six year olds ate 3.75 grams of salt a day, while teenagers between 13 and 17 ate 7.55 grams a day. Thirty-six percent of the sodium the children ate came from breads and cereals; meat products provided 19 percent and dairy products accounted for 11 percent. The American Heart Association recommends adults and children consume no more than 3.75 grams a day (about a teaspoon). Salt starts increasing the risk of high blood pressure in children starting at age one.

"Salt Intake of Children and Adolescents in South London: Consumption Levels and Dietary Sources. ", Hypertension, March 10, 2014

Debate Rages In Diet Industry Over “Cleansing” Products And Regimens

Physicians and nutritionists argue that the human body’s digestive system is already very efficient at removing harmful substances. But others – who are making millions of dollars selling detoxifying diets, diet books, supplements, juices, etc. – disagree, saying the liver, kidneys and colon are simply overwhelmed by the environmental toxins they have to deal with. And that’s the great debate in the $60 billion U.S. diet industry. Still, most gastroenterologists – acknowledging the confusion caused by the “jumble of science, pseudoscience and hype” of the cleansing industry – advise against the supplements, laxatives, enemas and irrigation devices sold to unclog the colon. For one thing, their use can lead ironically to constipation. Instead, eat more fruits and vegetables to keep the digestive system functioning normally.

"The Debate Over Juice Cleanses and Toxin Removal", The Wall Street Journal, March 03, 2014

 
Research, Studies, Advice  

Vitamin D Deficiency Among Children Not As Widespread Under New Guidelines

Thanks to revised Institute of Medicine guidelines on vitamin D deficiency, far fewer children in the U.S. are considered to have insufficient or deficient levels of vitamin D, a U.S. study has found. According to the new guidelines, most people get sufficient vitamin D when their blood levels are at or above 20 nanograms per milliliter (ng/mL). (Other guidelines recommend vitamin D levels above 30 ng/mL). The study looked at vitamin D data from 2,877 U.S. children and adolescents ages 6 to 18, finding that under the Institute of Medicine guidelines, 10.3 percent of children ages 6 to 18, or 5.5 million, are at risk. Under previous guidelines, millions more children who had vitamin D levels between 20 and 30 ng/mL would have needed supplementation.

"Prevalence of risk of deficiency and inadequacy of 25-hydroxyvitamin D in US children: NHANES 2003–2006. ", Journal of Pediatric Endocrinology and Metabolism, March 25, 2014

UV Exposure Reduces Folate Levels In Pregnant Women

Expectant mothers, and women who are trying to get pregnant, who are exposed to ultraviolet radiation may lose some of the health benefits of folate intake. An Australian study of 45 young healthy women aged 18 to 47 showed that high rates of sun exposure accounted for up to a 20 percent drop in folate levels. Folic acid is a B vitamin, and folate is found in green leafy vegetables, citrus fruits, legumes, etc. Folate has been found to reduce miscarriage and neural tube defects such as spina bifida in unborn babies. The women in the study who were most at risk were those outside between 10 a.m. and 3 p.m. with little sun protection.

"Exposure to solar ultraviolet radiation is associated with a decreased folate status in women of childbearing age. ", Journal of Photochemistry and Photobiology B: Biology, March 21, 2014

Anxiety, Depression Associated With Tooth Loss, Gum Disease

A study presented at a national dental meeting provides evidence that tooth and gum diseases, as well as other biosocial conditions, are closely associated with depression and anxiety. The study analyzed data on depression, anxiety and tooth loss collected in a 2010 telephone survey of 451,000 people aged 19 or older. Of the 76,292 eligible participants, 13.4 percent reported anxiety, 16.7 percent reported depression, and 5.7 percent reported total tooth loss. Careful cross-analysis found that people with dental anxiety often avoid dental care, while people who are depressed neglect their health, including dental health.

"Tooth loss linked to depression, anxiety", News release, study presented at the annual meeting of the American Association for Dental Research, March 20, 2014

Researchers Discover Possible Therapeutic Target For Type 2 Diabetes

U.S. researchers have found that by controlling levels of fat molecules called phosphatidic acids in the liver, it may be possible to reduce glucose production and control high blood sugar. The  University of Texas scientists, experimenting with mice, believe their findings could lead to the development of a drug that would help the estimated 25 million Americans with type 2 diabetes. In addition, the researchers believe their findings may help understand how cancer develops, because increased phosphatidic acid levels may play an important role in a metabolic pathway that supplies energy to cancer cells.

"Hepatic Gluconeogenesis Is Enhanced by Phosphatidic Acid Which Remains Uninhibited by Insulin in Lipodystrophic Agpat2-/- Mice. ", Journal of Biological Chemistry, March 19, 2014

No Evidence From Trials That Vitamin D Supplements Improve Depression Symptoms

Data from a systematic review of seven clinical trials involving 3,200 depression patients showed that vitamin D supplementation did little or nothing to improve symptoms. The U.S. researchers did find some hints in the data that vitamin D supplements may help patients with clinically significant depression, especially when combined with traditional antidepressant medication. The authors noted, however, that vitamin D supplements may be effective only for those who are already vitamin D deficient, and that future studies should consider how vitamin D dosing and mode of delivery affect depression.

"Vitamin D Supplementation for Depressive Symptoms: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. ", Psychosomatic Medicine, March 18, 2014

Sleep Loss Shown To Damage And Even Destroy Neurons

A U.S. study in mice found that chronic sleep loss may be more serious than previously thought, mainly because it may lead to irreversible damage to brain cells. Extended wakefulness in the lab animals led to significant loss of the locus coeruleus neurons essential for alertness and optimal cognition. The researchers stressed that more work needs to be done to determine whether a similar phenomenon occurs in humans and to determine how much sleep loss puts people at risk of neural injury.

"Extended Wakefulness: Compromised Metabolics in and Degeneration of Locus Ceruleus Neurons. ", Journal of Neuroscience, March 18, 2014

Proximity To Fast-Food Eateries Linked To Greater Risk Of Obesity

A British study finds that people who live or work near fast-food restaurants tend to be more obese than those whose access is more limited. The study, based on data from 5,442 adults aged 29-62, showed that when the three exposure possibilities (work, home and commute) were combined, there was a significant relationship between take-out exposure and food consumption. Those who lived or worked close to fast-food take-out outlets had higher body mass indexes. The researchers said that replacing fast-food restaurants with more healthful outlets probably wouldn’t work. But the food offered could be changed for the better because "in the food environment, what matters is the menu … not the venue”.

"Associations between exposure to takeaway food outlets, takeaway food consumption, and body weight in Cambridgeshire, UK: population based, cross sectional study. BMJ", BMJ, March 13, 2014

Older Men Who Eat More Animal Protein Experience Less Mental, Physical Decline

Life expectancy has increased steadily around the globe, but older people often lead lives plagued by mental and physical decline.  Researchers in Japan report that one way to combat  functional decline may be through  greater consumption of animal protein. With aging, the ability to absorb and process protein deteriorates. In their seven-year study, the researchers analyzed questionnaire data from 1,007 people whose average age was 67 years. Tests determined higher-level functional abilities  Men who consumed the most animal protein were 39 percent less likely to experience functional decline than those who ate the least animal protein. The association was not seen in women, nor were any benefits derived from eating plant protein in either sex.

"Animal Protein Intake Is Associated with Higher-Level Functional Capacity in Elderly Adults: The Ohasama Study", Journal of the American Geriatrics Society, March 11, 2014

Unless You’re Over 65, Eating A Lot Of Protein Increases Risk Of Cancer, Mortality

Two recent studies from the U.S. and Australia, one in mice and one in humans, found evidence that diets high in protein can actually be harmful over the long run. Protein-rich diets do have their benefits: they contribute to weight loss and to normalization of blood sugar levels. But the study in mice, which tested various ratios of protein to carbohydrates, found that animals that ate higher ratios of protein were leaner, but shorter-lived. The 18-year clinical study in 6,381 adults found that people aged 50 to 65 whose diet included high levels of animal protein were at much greater risk of cancer death and overall mortality. However, people over 65 who ate more animal protein survived longer. 

"The Risk of High-Protein Diets", The Wall Street Journal, March 10, 2014

Study Questions Fat and Heart Disease Link

New York Times, March 17, 2014

The Effects of Midlife Diet on Late-Life Cognition

Publications of the University of Eastern Finland, March 10, 2014

IHS: Focus on Prevention & Self Care

Nutraceuticals World, March 10, 2014

Why High-Impact Exercise Is Good for Your Bones

The New York Times Magazine, March 09, 2014

The Fat Drug

The New York Times, March 08, 2014

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