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Study Finds That Yogurt Consumption Significantly Cuts Risk Of Adult Diabetes

February 5, 2014: 12:00 AM EST
British researchers who analyzed dietary data collected from more than 25,000 men and women living in Norfolk, U.K., over 11 years, found that those who ate more low-fat fermented dairy products, including cottage cheese and yogurt, reduced the risk of type 2 diabetes by 24 percent. When the researchers focused on yogurt alone, which comprises 85 percent of fermented dairy products, they found a 28 percent reduced risk of diabetes.
Laura M. O’Connor et al., "Dietary dairy product intake and incident type 2 diabetes: a prospective study using dietary data from a 7-day food diary", Diabetologia, February 05, 2014, © O’Connor et al.
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Smokers Damaged By Smoking In Physical And Psychological Ways

February 4, 2014: 12:00 AM EST
Smoking is not only destructive and addictive, it also demotivates smokers from kicking the habit and moving to a healthier lifestyle, according to researchers in Brazil. Smokers are less physically active, lack motivation and are more likely to suffer symptoms of anxiety and depression. The study followed 60 smokers and 50 non-smokers who wore a pedometer for at least 12 hours a day for six days. Results showed that smokers walked less daily, their tested lung function was reduced and their ability to exercise in turn hampered. When asked to rate their health-related quality of life they said they felt more tired and lacked enthusiasm to change their inactive behavior.
Karina Couto Furlanetto et al., "Reduction of physical activity in daily life and its determinants in smokers without airflow obstruction", Respirology, February 04, 2014, © Furlanetto et al.
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Mediterranean Diet Linked To Lower Risk Of Cardiovascular Disease

February 4, 2014: 12:00 AM EST
An analysis of dietary questionnaire data provided by 780 U.S. firefighters finds that those who stuck to a modified Mediterranean diet (MMD) were less likely to have metabolic syndrome: a large waistline, high triglyceride levels, low HDL ("good") cholesterol levels, high blood pressure, or high blood sugar – all risk factors for cardiovascular disease. The U.S. researchers said the MMD firefighters showed a 35 percent decreased risk for metabolic syndrome, and also had a 43 percent lower risk of weight gain, compared to others. Consistent with previous research, obese participants in the firefighter study reported eating more fast foods and sugary drinks.
Justin Yang et al., "Modified Mediterranean Diet Score and Cardiovascular Risk in a North American Working Population", PLoS ONE, February 04, 2014, © Yang et al.
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Shiver And Shed Pounds, Study Suggests

February 4, 2014: 12:00 AM EST
A study conducted in the U.S. discovered how brown fat communicates with muscle via specific hormones. During exposure to cold – and especially when shivering for about 15 minutes – the hormone levels rise about the same amount as when exercising moderately for an hour. The hormones stimulate conversion of energy-storing “white fat” into energy-burning “brown fat”. About 50 g of white fat stores more than 300 calories of energy a day, while 50 g of brown fat burns 300 kilocalories a day. Transforming white fat into brown fat – by exercising or shivering – “could protect animals against diabetes, obesity and fatty liver”, the researchers said. And glucose levels are lower in humans with more brown fat.
Paul Lee et al., "Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans", Cell Metabolism, February 04, 2014, © Elsevier Inc.
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Vitamin C And E Supplementation Hinders Endurance During Athletic Training

February 3, 2014: 12:00 AM EST
Although it’s probably too late to help the Olympic athletes at Sochi, a finding by Norwegian researchers about the negative impact of vitamin E and C supplementation on endurance could help future competitors. An 11-week clinical study involved 54 young and healthy men and women randomly assigned to take vitamin C or vitamin E supplements, or a placebo. The participants were monitored closely as they took part in an endurance training program, mostly running. The study found that the vitamin C and E supplements seemed to blunt the improvement of muscle endurance by disrupting cellular adaptations in exercised muscles.
Paulsen G et al., "Vitamin C and E supplementation hampers cellular adaptation to endurance training in humans: a double-blind randomized control trial", Journal of Physiology, February 03, 2014, © The Physiological Society
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American Teens Consume Way Too Much Salt, Study Finds

February 3, 2014: 12:00 AM EST
Almost all adolescents in a cross-sectional U.S. study reported consuming double the amount of salt recommended daily, pretty much the same amount as adults, putting them in danger of obesity and damaging inflammation. Researchers gathered self-reported data from 766 healthy teenagers, finding that 97 percent exceeded the American Heart Association’s recommended daily intake of 1,500 mg of sodium. The study adjusted for what the teens ate and drank, and still found a correlation between salt intake and obesity. The high-sodium consumers also had high levels of a compound secreted by immune cells that contributes to chronic inflammation and to autoimmune diseases like lupus and arthritis.
H. Zhu et al., "Dietary Sodium, Adiposity, and Inflammation in Healthy Adolescents", Pediatrics, February 03, 2014, © American Academy of Pediatrics
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High-Protein Diet Is Risky Without Fruits And Vegetables

January 29, 2014: 12:00 AM EST
A Spanish study in rats shows that high-protein diets, like Dukan and Atkins, boost the risk of developing kidney problems, unless supplemented with fruits and vegetables. Animals on a high-protein diet lost as much as 10 percent of their body weight over the 12-week study, but the protein had a negative effect on kidney structure, a signal of an increased risk of kidney disease and serious pathologies like calcium kidney stones. High protein foods drastically reduce urinary citrate, an inhibitor of calcium salt crystallization and urinary pH. The researchers noted, however, that fruits and vegetables added to the diet reduce the risk of kidney stones forming. Why? Potassium and magnesium compensate for the acidity of the high-protein diet.
Aparicio VA et al., "High-protein diets and renal status in rats", Nutricion Hospitalaria, January 29, 2014, © Nutricion Hospitalaria
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Epilepsy Drug May Someday Be Used To Treat Fatty Liver Disease, Metabolic Disorders

January 29, 2014: 12:00 AM EST
An anticonvulsant drug commonly prescribed to treat epilepsy may someday be used to reduce fat accumulation in the liver and control blood sugar levels. Valproic acid (Depakote), tested in obese mice, activates a protein (AMPK) previously shown to be a good drug target for treating type 2 diabetes and obesity. They found that valproic acid activates AMPK in mouse and human liver cells in a dose-dependent way. Further research found that the byproducts of valproic acid metabolism, as opposed to valproic acid itself, were the molecules activating AMPK. “That's a desirable quality if you want to eventually use it to treat people," the U.S.researchers noted.
L. B. Avery et al., "Valproic Acid Is a Novel Activator of AMP-Activated Protein Kinase and Decreases Liver Mass, Hepatic Fat Accumulation, and Serum Glucose in Obese Mice", Molecular Pharmacology, January 29, 2014, © The American Society for Pharmacology and Experimental Therapeutics
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Probiotics Supplements Help Women – But Not Men – Lose Weight

January 28, 2014: 12:00 AM EST
Canadian researchers have found in a clinical study that women who took probiotics supplements in pill form lost twice as much weight as women in a non-probiotic control group. Probiotics supplements had no impact on the weight of men in the study, however, a finding that baffled the researchers. The study was conducted among 125 overweight men and women over 24 weeks. The average weight loss was 5.6 kg in women in the probiotic group and 2.6 kg in the placebo group. According to the lead researcher, probiotics may act by altering the permeability of the intestinal wall, keeping certain pro-inflammatory molecules from entering the bloodstream and causing a chain reaction that leads to glucose intolerance, type 2 diabetes, and obesity.
Marina Sanchez et al., "Effect of Lactobacillus rhamnosus CGMCC1.3724 supplementation on weight loss and maintenance in obese men and women", British Journal of Nutrition, January 28, 2014, © Cambridge University Press
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Vitamin D2 Supplementation Worsens Muscle Damage From Heavy Lifting

January 27, 2014: 12:00 AM EST
Research conducted at a North Carolina university found that “power athletes” – intense weight lifters and auto racing pit crews, for example –  would be better off staying away from vitamin D2 supplements. The study was conducted among NASCAR pit crew athletes, half of whom consumed 3,800 international units (IU) a day of a plant-based vitamin D2, the other half a placebo. The researchers thought taking vitamin D2 would reduce inflammation and speed recovery of muscle damage from heavy lifting. Instead, the supplement increased exercise-induced muscle damage in the pit crew athletes.
David Nieman et al., "Vitamin D2 Supplementation Amplifies Eccentric Exercise-Induced Muscle Damage in NASCAR Pit Crew Athletes", Nutrients, January 27, 2014, © MDPI AG
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Scientists Discover What Works Best At Preventing, Treating The Common Cold

January 27, 2014: 12:00 AM EST
Canadian scientists who reviewed studies that evaluated traditional and nontraditional approaches to dealing with the common cold found a variety of ways to both prevent and treat the annoying wintertime ailment. It’s an important consideration, considering that in the U.S. in 1997, direct medical costs (i.e., doctor visits, treating secondary infections, medications, etc.) were $17 billion, while indirect costs (missed work, etc.) totaled $25 billion. The researchers found that hand washing, zinc and possibly probiotics may be most effective at preventing a cold, while acetaminophen, ibuprofen and perhaps antihistamine-decongestant combinations were the best treatments.
G. Michael Allan and Bruce Arroll, "Prevention and treatment of the common cold: making sense of the evidence", CMAJ, January 27, 2014, © Canadian Medical Association
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Scientists Shed Light On How Ancient Wound Treatment Works At The Molecular Level

January 24, 2014: 12:00 AM EST
German researchers have discovered the molecular basis of the age-old healing action of birch bark. In phase one of healing, an extract of the bark, and its main ingredient betulin, temporarily increases inflammatory substances released by damaged skin cells by activating proteins that extend the half-life of the messenger ribonucleic acid (mRNA). Healing proceeds to a second phase, in which the birch extract (with betulin and lupeol) speeds up proteins involved in the restructuring of the actin cytoskeleton, which gives skin cells their shape. The cells then migrate to the wound and close it, completing the healing process. 
Sandra Ebeling et al., "From a Traditional Medicinal Plant to a Rational Drug: Understanding the Clinically Proven Wound Healing Efficacy of Birch Bark Extract", PLoS ONE, January 24, 2014, © Ebeling et al.
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Animal Study Finds Hope For Dietary Treatment For Alzheimer’s

January 24, 2014: 12:00 AM EST
A study in mice finds that even slight changes in the diet of Alzheimer’s patients may, if adopted early and for a long period of time, lead to significant changes in brain metabolism and improved memory. The researchers tested the effects of a fish oil-enriched diet, a plant sterol diet, and a commercially available supplement known as Fortasyn. The diets led to improvements in different ways, including memory and plaque formation, The Finnish researchers concluded that a single cocktail of nutrients would probably not provide the best outcome at this time. But further research, especially in humans, may lead to development of a diet-based treatment for Alzheimer's disease.
Hennariikka Koivisto et al., "Special lipid-based diets alleviate cognitive deficits in the APPswe/PS1dE9 transgenic mouse model of Alzheimer's disease independent of brain amyloid deposition", Journal of Nutritional Biochemistry, January 24, 2014, © Elsevier Inc.
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Parkinson’s Patients Benefit From Intense Strength Training

January 24, 2014: 12:00 AM EST
A four-month clinical study involving 15 Parkinson’s patients found that high-intensity resistance training combined with interval training not only improved strength, muscle size and power – which was not surprising – but also improved balance, muscle control, cognition, mood and a sense of well-being. Muscle biopsies taken at the start and conclusion of the study showed positive changes in skeletal muscle at the cellular and subcellular levels associated with improvements in motor function and physical capacity. Strength training produces a major improvement in the ability to activate muscles, generate power and produce energy, the U.S. researchers said, "all of which can contribute to improved quality of life and reduction of injury risk from falls" among Parkinson’s patients.
N. A. Kelly et al., "Novel, High-Intensity Exercise Prescription Improves Muscle Mass, Mitochondrial Function, And Physical Capacity In Individuals With Parkinson's Disease", Journal of Applied Physiology, January 24, 2014, © Journal of Applied Physiology
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Impulsive Behavior Linked To Food Addiction, And To Obesity

January 24, 2014: 12:00 AM EST
People with impulsive personalities are more likely to report higher levels of food addiction and obesity, a U.S. study has found. Food addiction, a relatively new disorder, is a compulsive pattern of eating similar to drug addiction. The study used two different scales to determine levels of food addiction and impulsivity among the 233 participants, then compared these results with body mass index, a measure of obesity. Researchers said impulsive behavior was not necessarily associated with obesity, but impulsive behaviors can lead to food addiction, which is an indicator of obesity.
Cara M. Murphy et al., "Interrelationships among impulsive personality traits, food addiction, and Body Mass Index", Appetite, January 24, 2014, © Elsevier B.V.
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Omega-3 Fatty Acids Benefit Liver Metabolism In Many Unforeseen Ways, Study Finds

January 23, 2014: 12:00 AM EST
Omega-3 fatty acids – especially DHA – could be significantly effective in preventing fatty liver disease and other metabolic problems caused by the Western diet, according to scientists at Oregon State University. In a study in mice that used a technology known as “metabolomics”, DHA supplements produced many unanticipated benefits, including changes in vitamin and carbohydrate metabolism, protein and amino acid function and lipid metabolism. DHA supplementation prevented metabolic damage caused by the Western diet: excessive consumption of red meat, sugar, saturated fat and processed grain.
Christopher M. Depner et al., "A Metabolomic Analysis of Omega-3 Fatty Acid-Mediated Attenuation of Western Diet-Induced Nonalcoholic Steatohepatitis in LDLR-/- Mice", PLoS ONE, January 23, 2014, © Depner et al.
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Lingonberries Prevent Weight Gain, Lower Blood Sugar And Insulin, In Animal Study

January 23, 2014: 12:00 AM EST
The Scandinavian fruit lingonberries prevented weight gain in mice that ate a high-fat diet, a Swedish study reports. The berries also reduced blood sugar and cholesterol levels. Lingonberries were tested against other berries: bilberry, raspberry, crowberry, blackberry, prune, blackcurrant or açai berry in mice fed high-fat and low-fat diets. After three months, the lingonberry group had not put on more weight than the low-fat mice, their blood sugar and insulin readings were similar, and cholesterol levels and levels of fat in the liver were lower. Blackcurrants and bilberries also produced good effects, though not as pronounced as the lingonberries, researchers said.
Lovisa Heyman et al., "Evaluation of Beneficial Metabolic Effects of Berries in High-Fat Fed C57BL/6J Mice", Journal of Nutrition and Metabolism, January 23, 2014, © Heyman et al.
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Small Elliptical Device Provides An Answer To Weight Gains From Sedentary Lifestyle

January 22, 2014: 12:00 AM EST
Sedentary Americans – those who spend on average 11 hours a day watching TV or using a computer – would definitely benefit from using a small elliptical machine every day, a U.S. study finds. Thirty-two participants in the study used a small elliptical device while sitting in a standard office chair. Measurements of calories burned, heart rate and other biometrics found that 86 percent burned enough calories in an hour to prevent weight gain. The other 14 percent would have accomplished the same had they pedaled a little faster. Daily use of the elliptical device for an hour might result in a weight loss of 5.2 pounds per year.
Liza S. Rovniak et al., "Feasibility of using a compact elliptical device to increase energy expenditure during sedentary activities", Journal of Science and Medicine in Sport, January 22, 2014, © Sports Medicine Australia
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Higher Levels Of Omega-3s In Blood Prevents Brain Shrinkage From Aging, Disease

January 22, 2014: 12:00 AM EST
A long-term clinical study of 1,111 women by U.S. researchers shows that people with higher levels of the omega-3 fatty acids found in fish oil may tend to have larger brain volumes as they age, preserving one to two years of brain health. One of the signs of Alzheimer’s disease – and normal aging – is a decrease in brain volume. Researchers measured levels of omega-3 fatty acids EPA and DHA in red blood cells in the women, following up eight years later with an MRI to measure brain volume. By that time, the women – average age of 78 – with levels of fatty acids twice that of other women had a 0.7 percent larger brain volume.
J. V. Pottala et al., "Higher RBC EPA DHA corresponds with larger total brain and hippocampal volumes", Neurology, January 22, 2014, © American Academy of Neurology
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Physical Activity Reduces Heart Failure Risk In Men, Large Clinical Study Finds

January 21, 2014: 12:00 AM EST
Sitting around too much – i.e., the sedentary lifestyle – greatly increases the risk of heart failure, a U.S. study has found. Researchers tracked a racially diverse group of 84,170 men ages 45 to 69 without heart failure for eight years, measuring exercise levels as well as hours spent just sitting around. Men with low levels of physical activity were 52 percent more likely to develop heart failure than men with high physical activity levels, even after adjusting for differences in sedentary time. Preventing heart failure requires a two-part behavioral approach: high levels of physical activity plus low levels of sedentary time. "Be more active and sit less. That's the message here," the researchers concluded.
D. R. Young et al., "Effects of Physical Activity and Sedentary Time on the Risk of Heart Failure", Circulation: Heart Failure, January 21, 2014, © American Heart Association, Inc.
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Celiac Patients Tolerate Quinoa Added To Gluten-Free Diet

January 21, 2014: 12:00 AM EST
Despite evidence from lab experiments that the nutritious grain quinoa can cause some digestive problems for celiac disease patients, a new British study in patients themselves shows that the grain, when added to a gluten-free diet, is actually well-tolerated and does not worsen the condition. Celiac is an immune-based reaction to gluten, a protein found in wheat, barley and rye. The new study, which tracked 19 celiac patients over six weeks, shows that eating about 50 grams of quinoa every day led to normal blood test ranges, and even improved the structure of the small intestine. Patients were allowed to cook the grain any way they wished.
Victor F Zevallos et al., "Gastrointestinal Effects of Eating Quinoa (Chenopodium quinoa Willd.) in Celiac Patients", The American Journal of Gastroenterology, January 21, 2014, © The American College of Gastroenterology
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Fortified Mediterranean Diet Cuts Risk Of Artery-Blocking Disease

January 21, 2014: 12:00 AM EST
A seven-year clinical trial conducted in Spain among more than 7,000 men and women over age 55 has found a significant association between a fortified Mediterranean diet and a lower risk of peripheral artery disease (PAD). In peripheral arterial disease plaque – fat, cholesterol, calcium, etc. – builds up in the arteries that carry blood to the head, organs, and limbs, leading to atherosclerosis (hardening). The study confirmed that a Mediterranean diet fortified either with extra virgin olive oil or nuts reduced the risk of PAD in participants.
Miguel Ruiz-Canela et al., "Association of Mediterranean Diet With Peripheral Artery Disease", JAMA, January 21, 2014, © American Medical Association
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Researchers Determine Why A Fiber-Rich Diet Reduces Risk Of Colon Inflammation, Cancer

January 16, 2014: 12:00 AM EST
U.S. researchers have determined that a high-fiber diet cuts the risk of colon problems because fiber – which supports good bacteria in the gut – activates a receptor that helps prevent colon inflammation and cancer (while protecting the cardiovascular system).  The same receptor is activated by high levels of niacin, administered by doctors when a patient has abused antibiotics, destroying beneficial bacteria. Good bacteria in the colon thrive on fiber and its digestion produces butyrate, a fatty acid that naturally activates the receptor, Gpr109a. The relationship is limited to the colon, where butyrate levels can soar with a high-fiber diet.
Nagendra Singh et al., "Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis", Immunity, January 16, 2014, © Elsevier Inc.
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“Diet” Sodas Actually Work Against A Dieter’s Weight Loss Plan

January 16, 2014: 12:00 AM EST
Drinking diet soda is not the answer to losing weight, according to U.S. scientists who analyzed national data and determined that artificial sweeteners activate reward centers in the brain in a way that causes the sweet sensors to malfunction. The brain's sweet sensors can’t gauge energy consumption accurately because the artificial sweeteners disrupt appetite control, resulting in increased food intake overall. Bottom line: overweight and obese adults who drink diet beverages consume more calories from food than obese or overweight adults who drink regular soda or other sugary beverages.
Sara N. Bleich et al., "Diet Beverage Consumption and Caloric Intake Among US Adults Overall and by Body Weight", American Journal of Public Health, January 16, 2014, © American Public Health Association
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Vitamin D Associated With Milder Parkinson’s Disease Symptoms

January 16, 2014: 12:00 AM EST
Higher levels of vitamin D in the blood of Parkinson’s disease patients are associated with less severe symptoms, especially among patients who are not suffering from dementia, a U.S. study finds. Investigators tested  286 patients with Parkinson’s, finding that all patients with higher plasma vitamin D levels had lower symptom severity, better cognition, and less depression, but the relationships were even stronger in those who were not demented. Of the 286 subjects, 61 were considered to be demented. The researchers found that higher levels of serum vitamin D3 in the non-demented patients were associated with greater fluency for naming vegetables and animals, and immediate and delayed recall on a verbal learning test.
Amie L. Peterson et al., "Memory, Mood, and Vitamin D in Persons with Parkinson’s Disease", Journal of Parkinson’s Disease, January 16, 2014, © IOS Press
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More Good News About Omega-3s: Reduced Risk Of Type 2 Diabetes

January 15, 2014: 12:00 AM EST
A Finnish university study finds that high blood levels of long chain omega-3  fatty acids – found in fish and fish oils – are associated with a significantly reduced risk of type 2 diabetes in men. The study collected dietary data on 2,212 men between 42 and 60 years of age, beginning in 1984. Thhose with the highest concentrations of omega-3s in their blood were 33 percent less likely to develop type 2 diabetes. Along with weight management, exercise, and a well-rounded diet, the researchers recommended at least two fish meals a week, preferably fatty fish like salmon, rainbow trout, herring, anchovy, sardine or mackerel.
Jyrki K. Virtanen et al., "Serum Omega-3 Polyunsaturated Fatty Acids and Risk of Incident Type 2 Diabetes in Men", Diabetes Care, January 15, 2014, © American Diabetes Association
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Fast Food Diet Is A Symptom Of The Childhood Obesity Problem, Not The Cause

January 15, 2014: 12:00 AM EST
Eating fast food is not the root cause of the childhood obesity problem, as some have suggested, but only a symptom of a deeper problem that begins at home, according to researchers at the University of North Carolina who examined data collected on 4,466 children who two years to 18 years of age. In other words, it’s basically the parents’ fault. Kids do not eat adequate amounts of fruits and vegetables as they’re growing up, chowing down instead on large amounts of processed food and sugar-sweetened beverages. These meal patterns are in turn enforced at school. “This is what is really driving children’s obesity,” concluded one researcher.
J. M. Poti et al., "The association of fast food consumption with poor dietary outcomes and obesity among children: is it the fast food or the remainder of the diet?", American Journal of Clinical Nutrition, January 15, 2014, © American Society for Nutrition
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Vitamin E Slows Functional Decline Among Alzheimer’s Patients

January 9, 2014: 12:00 AM EST
A U.S. study finds evidence that vitamin E slows functional decline in patients with mild-to-moderate Alzheimer’s disease, though no added benefit for memory or cognitive testing was discerned. The clinical study involved 613 patients with mild-to-moderate Alzheimer's and was conducted from August 2007 to September 2012 at 14 Veterans Affairs Medical Centers. The trial showed that vitamin E delays progression of functional decline by 19 percent a year, which translates into 6.2 months benefit over placebo. Alzheimer's affects 5.1 million Americans and is a taxing burden on 5.4 million family members and friends who serve as caregivers.
Maurice W. Dysken et al., "Effect of Vitamin E and Memantine on Functional Decline in Alzheimer Disease", JAMA, January 09, 2014, © American Medical Association
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Algal Culture Extract Shown To Increase Good Cholesterol, Even In High-Fat Diet

January 9, 2014: 12:00 AM EST
A proprietary algal culture – known as “PAZ” or “ProAlgaZyme” – was found to support healthy cholesterol balance by increasing “good” cholesterol (HDL) and reducing non-HDL cholesterol while consuming a high-fat diet. The testing in lab animals showed that PAZ helped remove excess cholesterol from cell storage and transported it to the liver for excretion from the body. Health Enhancement Products, Inc., maker of the algal culture extracts, says  the effects of its product in improving "good" cholesterol, and therefore cardiovascular health, “are significant and potentially wide-reaching”.
Smiti Gupta et al., "ProAlgaZyme sub-fraction improves the lipoprotein profile of hypercholesterolemic hamsters, while inhibiting production of betaine, carnitine, and choline metabolites", Journal of Nutrition & Metabolism, January 09, 2014, © Geamanu et al.
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Conclusions Drawn From Multivitamin Studies Are Useless, Thanks To Flawed Methodologies

January 8, 2014: 12:00 AM EST
Poor methodology used in large clinical studies probing the value of vitamin supplements has rendered them mostly useless, according to U.S. scientists. Whether the studies defend or disparage the use of multivitamin and other micronutrient supplements, flaws in study design torpedo their value. Many studies have tried to analyze nutrients that are naturally available in the human diet the same way they would a powerful prescription drug, leading  to conclusions that have little scientific meaning, even less accuracy and often defy a wealth of other evidence, said one researcher. What is needed are new methodologies that accurately measure baseline nutrient levels, provide supplements or dietary changes only to participants who clearly are inadequate or deficient, and then study the resulting changes in their health.
Alexander Michels et al., "Myths, Artifacts, and Fatal Flaws: Identifying Limitations and Opportunities in Vitamin C Research", Nutrients, January 08, 2014, © MDPI AG
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Healthy Sleep Promotes A Healthy Brain, Study Finds

January 8, 2014: 12:00 AM EST
One night of sleep deprivation increases morning concentrations of molecules that signal a decline in brain tissue, Swedish scientists have found. For the study, fifteen normal-weight men were sleep-deprived for one night, and then slept a normal eight hours. A night of total sleep loss was followed by increased blood concentrations of NSE and S-100B, brain molecules that typically rise in blood under conditions of brain damage. “Our results indicate that a lack of sleep may promote neurodegenerative processes,” the researchers concluded, “ and “a good night’s sleep may be critical for maintaining brain health.”
Christian Benedict et al. , "Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men", Sleep, January 08, 2014, © Associated Professional Sleep Societies, LLC
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Higher Levels Of All Forms Of Vitamin E Protect Against Memory Disorders In Elderly

January 7, 2014: 12:00 AM EST
There are eight natural forms of vitamin E – from tocopherols to tocotrienols. All of them have antioxidant properties and all seem to play a role in memory processes, according to a Finnish study. Researchers in fact found that elderly people with higher levels of the various forms of vitamin E in their blood are less at risk for memory disorders. The eight-year study followed 140 people aged 65 or older who had no memory problems at the start. After eight years, those with higher total serum levels of γ-tocopherol, β-tocotrienol and total tocotrienols, suffered less from memory disorders.
Francesca Mangialasche et al., "Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults", Experimental Gerontology, January 07, 2014, © Elsevier Inc.
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Key To Keeping Weight Off Is Maintaining Healthy Behaviors

January 6, 2014: 12:00 AM EST
It is possible for people to keep off the weight they have lost if they continue to pursue healthy behaviors, especially physical activity, self-weighing, low-fat diet and avoiding overeating. The observational U.S. study involved nearly 3,000 participants who had lost at least 30 pounds and had kept it off for at least a year. The participants were followed for ten years. On average, participants kept most of the weight off during the ten years. Decreases in physical activity, dietary restraint and self-weighing along with increases in fat intake were associated with greater weight regain.
J. Graham Thomas et al., "Weight-Loss Maintenance for 10 Years in the National Weight Control Registry", American Journal of Preventive Medicine, January 06, 2014, © American Journal of Preventive Medicine
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Fiber-Rich Diet Reduces Risk Of Asthma, Study FInds

January 6, 2014: 12:00 AM EST
A Swiss study finds that the risk of developing asthma rises if a person’s diet lacks the fiber found in fruits and vegetables. The immune response in the lungs is influenced by the fatty acids in the blood stream created when intestinal bacteria ferment dietary fiber. The study conducted in mice shows that a lack of fermentable fibers in the diet paves the way for allergic inflammatory reactions in the lungs. The problem is growing in areas of the world where the Western diet prevails because fruit and vegetables are playing an ever smaller role in people's diets.
Aurélien Trompette et al., "Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis", Nature Medicine, January 06, 2014, © Nature Publishing Group
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Organic Milk Shown To Be Much Heart-Healthier Than Conventional Milk

January 3, 2014: 12:00 AM EST
Organic milk contains significantly higher concentrations of heart-healthy fatty acids than milk from cows fed conventionally, U.S. researchers report. The study compared 400 samples of organic and conventional milk over 18 months. The researchers were surprised to find that conventional milk had an average omega-6 to omega-3 fatty acid ratio of 5.8, more than twice that of organic milk's ratio of 2.3. The heart-healthier ratio of fatty acids in organic milk is due to a greater reliance on pasture and forage-based feeds – grass and legumes – on organic dairy farms.
Charles M. Benbrook et al., "Organic Production Enhances Milk Nutritional Quality by Shifting Fatty Acid Composition", PLoS ONE, January 03, 2014, © Benbrook et al.
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Chinese Herbal Medicine Offers Hope To People In Serious Pain

January 3, 2014: 12:00 AM EST
Chronic neuropathic pain from conditions such as diabetes and multiple sclerosis affects more than 50 million Americans, but so far conventional analgesics with their often severe side affects have not provided relief. Now Chinese and U.S. scientists have determined in rodent research that a compound derived from a traditional Chinese herbal medicine alleviates pain. Dehydrocorybulbine (DHCB) from the roots of the Corydalis yanhusuo plant relieved both inflammatory pain from tissue damage and injury-induced neuropathic pain caused by damage to the nervous system. The compound may point the way to an effective and non-addictive neuropathic pain reliever.
Yan Zhang et al., "A Novel Analgesic Isolated from a Traditional Chinese Medicine", Current Biology, January 03, 2014, © Elsevier Inc.
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Obesity Epidemic Not Just A Western Phenomenon

January 3, 2014: 12:00 AM EST
A British think tank reports that more than a third of adults globally were overweight or obese in 2008, a 23 percent increase from 1980. Adults in the developing world did not escape the phenomenon, of course: over the last 30 years, obese adults in these countries quadrupled to 904 million, more than are found in the developed countries. But the surprise is how the trend has invaded emerging economies. According to the Overseas Development Institute, the increase in  obesity is associated with a "creeping homogenization" of diets globally, thanks to rising incomes, the impact of advertising and globalization.
Sharada Keats and Steve Wiggins, "Future diets: Implications for agriculture and food prices", Overseas Development Institute, January 03, 2014, © Overseas Development Institute
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Fortified Indian Snack May Help Solve India’s Child Nutrition Problem

January 2, 2014: 12:00 AM EST
A nutrient-dense version of a traditional Indian snack could go a long way toward relieving the child malnutrition problem in the country. About 45,000 children die of malnutrition in the state of Maharashtra each year. In a recent pilot study, half of the participating children were diagnosed as severely malnourished. For the study, a researcher developed a recipe for laddoos, donut-hole shaped snacks served at Indian festivals, consisting of whole wheat flour, roasted peanuts, milk, cardamom, butter, sesame seed, and cane juice pressed into cakes. During the study, more than half of the children who regularly ate the fortified laddoos went from severely malnourished to moderately malnourished.
Sydney Brownstone , "A Small, Round Indian Dessert With Hidden Malnutrition-Fighting Powers", Co.Exist, January 02, 2014, © Mansueto Ventures, LLC
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Daily Exercise Erases Deleterious Effects Of Over-Eating, Lounging

December 27, 2013: 12:00 AM EST
A British study involving 26 healthy, active young men who were asked to do “a lot of sitting and gorging themselves” for seven days found that those who stopped exercising completely experienced a significant, unhealthy decline in blood sugar control. In addition, their fat cells began over-expressing certain genes associated with unhealthy metabolic changes while under-expressing genes linked to a healthy metabolism. Participants who continued to exercise daily – even though they upped their calorie intake – were not affected the same way. Blood sugar control and fat cell gene expression remained normal, compared to the sedentary men.
Gretchen Reynolds, "The Power of a Daily Bout of Exercise", The New York Times, December 27, 2013, © The New York Times Company
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Allergy Rates Lower Among Children Whose Moms Ate Peanuts While Pregnant

December 23, 2013: 12:00 AM EST
Contrary to traditional medical opinion, pregnant women should not worry that eating peanuts will cause a peanut allergy in their child, U.S. researchers report. For years women were advised to avoid highly allergenic foods such as peanuts and tree nuts during pregnancy and while nursing. In addition, it was suggested that children three years old and younger should not be allowed to eat peanuts. The researchers noted that despite the advice, from 1997 to 2007 the number of peanut allergy cases in the U.S. tripled. Researchers analyzed data collected from  8,205 children, finding that peanut allergy rates were significantly lower among children whose mothers ate peanuts before and during pregnancy.
A. Lindsay Frazier et al., "Prospective Study of Peripregnancy Consumption of Peanuts or Tree Nuts by Mothers and the Risk of Peanut or Tree Nut Allergy in Their Offspring", JAMA Pediatrics, December 23, 2013, © American Medical Association
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Harmful Dietary Supplements Contribute To Alarming Rise In Drug-Related Liver Injuries In U.S.

December 21, 2013: 12:00 AM EST
Drug-related liver injuries are on the rise, thanks to increased use of dietary supplements, a $32 billion industry in the U.S. largely unregulated and built on often-unproven claims that products will help people lose weight, build muscle or ward off a host of chronic illnesses. According to new U.S. research, dietary supplements account for nearly 20 percent of drug-related liver injuries serious enough to require hospital care. That’s a seven percent increase, and may actually undercount the total number of cases. Studies show that the market has been deluged with adulterated and mislabeled products, and products packaged in potentially unsafe dosages.
The supplement industry says most products are safe, but acknowledges that harmful, contaminated products – often bodybuilding supplements tainted with steroids – are sold by a “criminal” fringe of suppliers.
Anahad O’Connor, "Spike in Harm to Liver Is Tied to Dietary Aids", The New York Times, December 21, 2013, © The New York Times Company
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CDC Says That, Except For Young Kids, Most Americans Still Consume Too Much Salt

December 20, 2013: 12:00 AM EST
The Centers for Disease Control and Prevention’s report on eight years of data (2003 – 2010) on sodium intake in the U.S. says there were small declines in the prevalence of excess sodium intake among children through age 13, but none in adolescents or adults. “Despite slight declines in some groups, the majority of the U.S. population aged greater than or equal to one year consumes excess sodium,” the CDC notes. The agency adds that reducing sodium intake is a national health priority because excess sodium intake can lead to hypertension, a risk factor for cardiovascular disease.
"Trends in the Prevalence of Excess Dietary Sodium Intake — United States, 2003–2010 ", Report, Centers for Disease Control and Prevention, December 20, 2013, © Centers for Disease Control and Prevention
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Body’s Circadian Rhythms Upset By High-Fat Diet, Causing Metabolic Problems

December 19, 2013: 12:00 AM EST
The circadian clock – the internal body clock that regulates metabolic functions in the liver – can reprogram itself depending on the nutritional content, especially the fat content, of a person’s diet, U.S. researchers report. The day-night pattern of circadian rhythms affects about 15 percent of human genes, including those involved with metabolic pathways in the liver. A high-fat diet reprograms the liver clock, contributing to ailments such as diabetes, obesity and high blood pressure. The researchers noted, however, that returning to a balanced, low-fat diet normalizes the rhythms. The findings could lead to the discovery of drug targets for controlled diets.
Kristin L. Eckel-Mahan et al., "Reprogramming of the Circadian Clock by Nutritional Challenge", Cell, December 19, 2013, © Elsevier Inc.
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African-American Women Need To Exercise More, Eat Less Than Caucasians To Lose Weight

December 19, 2013: 12:00 AM EST
Researchers who looked for metabolic reasons why African-American women don’t lose as much weight as white women when they diet or exercise have found that the African-American women had lower resting metabolic rates and generally expended less energy during activity. That means that to lose weight they need to eat fewer – and burn more – calories than Caucasian women. The U.S. study was conducted among 39 severely obese African-American and 66 Caucasian women who participated in a six-month weight loss program. The African-American women lost about seven pounds fewer than the Caucasian women, even though their starting body mass index, or BMI, measures were comparable and they consumed the same number of calories and exercised the same way.
J P DeLany et al., "African American women exhibit similar adherence to intervention but lose less weight due to lower energy requirements", International Journal of Obesity, December 19, 2013, © Nature Publishing Group
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Tomato-Rich Diet Reduces Risk Of Breast Cancer In Post-Menopausal Women

December 18, 2013: 12:00 AM EST
U.S. researchers who conducted a longitudinal cross-over study examining the effects of diet on 70 postmenopausal women found that a tomato-rich diet may help protect against breast cancer. A diet rich in tomatoes had a larger impact on the levels of hormones that regulate fat and sugar metabolism in women who maintained a healthy weight, the researchers said. Breast cancer risk rises in postmenopausal women as their body mass index climbs. With the tomato-rich diet, participants' levels of the hormone adiponectin climbed nine percent.
Adana Llanos et al., "Effects of Tomato and Soy on Serum Adipokine Concentrations in Postmenopausal Women at Increased Breast Cancer Risk", Journal of Clinical Endocrinology & Metabolism, December 18, 2013, © The Endocrine Society
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Skip The Supplements, Stick To Nutrient-Rich Foods, Studies Advise

December 17, 2013: 12:00 AM EST
Dietary supplements may help some people with special nutrient needs, but generally eating a variety of nutrient-rich foods is the best way to get healthy nutrients needed to reduce the risk of chronic disease, U.S. studies have found. The studies, along with an accompanying editorial, say there really is not clear benefit for most healthy people to take vitamin supplements. Choosing foods that provide the most nutrients per calorie “can build a healthier life and start down a path of health and wellness”. Recommendations include a healthy breakfast, whole grains, fresh or frozen fruits and vegetables, omega 3-rich seafood and fiber- and folate-rich beans.
Eliseo Guallar et al., "Enough Is Enough: Stop Wasting Money on Vitamin and Mineral Supplements", Annals of Internal Medicine, December 17, 2013, © American College of Physicians.
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Daily Apple – Or Statin – Equally Likely To Keep The Doctor Away

December 17, 2013: 12:00 AM EST
Eating just one apple a day would prevent or delay around 8,500 vascular deaths such as heart attacks and strokes every year among adults over age 50 in the U.K., a British study has found. The same result could also be achieved, perhaps with more side effects and complications like muscular myopathy, by taking statins each day. The researchers used mathematical models to analyze the effect of eating an apple a day on common causes of “vascular mortality”. Subjects in the study did not already take statins. A daily statin given to 17.6 million more adults would reduce vascular deaths by 9,400 a year, while a daily apple given to 22 million Britons over 50 years would prevent 8,500 vascular deaths.
A. D. M. Briggs et al., "A statin a day keeps the doctor away: comparative proverb assessment modeling study", BMJ, December 17, 2013, © Briggs et al.
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TV Ads Seen By Kids In 2009 Touted Unhealthful Foods, Drinks

December 17, 2013: 12:00 AM EST
Foods and drinks advertised on TV programs – both children’s and others – in 2009 were generally less nutritious than foods promoted during regular broadcast hours, according to a new U.S. study. Researchers analyzed Nielsen TV ratings data from 2009 to determine what kind of food advertising children were exposed to. They then analyzed the nutritional content of the foods advertised on shows with a child-audience share of 35 percent of greater. More than 84 percent of food and beverage ads seen by children, ages 2 to 11, on all programming touted products high in fats, sugars and sodium. On children's programming, more than 95 percent of ads were for products high in those unhealthy ingredients.
Lisa Powell et al. , "Nutritional Content of Food and Beverage Products in Television Advertisements Seen on Children's Programming", Childhood Obesity, December 17, 2013, © Mary Ann Liebert, Inc.
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Newly Patented Compound Shows Promise In Treating Obesity

December 16, 2013: 12:00 AM EST
U.S. researchers have been awarded a patent for an antioxidant compound that, in mice, decreases obesity by breaking down triglycerides stored in fat tissue. The compound could someday be used to treat obesity and related disorders like type 2 diabetes in humans. According to the researchers, obese mice that ingested the compound lost 40 percent of their body weight. The next step is to figure out how the compound, MnTBAP, triggers cellular and molecular events that lead to the weight loss, the Skidmore College researchers say.
Jonathan R. Brestoff Parker & Thomas H. Reynolds, "Researchers Earn Patent of Use for Anti-obesity Compound", News release, Skidmore College (N.Y.), December 16, 2013, © Skidmore College
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Outer Ear Acupuncture Effective At Reducing BMI, Abdominal Fat

December 16, 2013: 12:00 AM EST
Korean researchers who looked at the impact of outer ear acupuncture on weight loss found that  five points seemed to reduce abdominal fat a little better than only one point. During the eight-week study, 91 overweight participants followed a careful, but not a weight loss, diet without extra exercise, and received either 5-point, 1-point or sham acupuncture treatment. Significant differences were apparent after four weeks: active treatment groups showed a 6.1 percent (5-point treatment) in BMI and reduction in abdominal fat, while 5.7 percent (1-point treatment) experienced a reduction in BMI. The sham treatment group experienced no reduction in BMI.
S. Yeo et al., "Randomised clinical trial of five ear acupuncture points for the treatment of overweight people", Acupuncture in Medicine, December 16, 2013, © British Medical Acupuncture Society
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